A. Alp Yetisgin, PhD


A. Alp Yetisgin

Welcome — thanks for finding your way here.

I am a PhD-level materials scientist and bioengineer working at the interface of biomaterials, microphysiological testbeds, and translational validation. I build simple, decision-oriented experimental systems to answer hard questions about material–biointerface performance: adhesion, wetting, transport, mechanics, and biological response. My background spans polymer chemistry and soft matter (hydrogels, polymersomes, nanogels), bioceramics (hydroxyapatite composites), and microfluidic lab-on-chip platforms, supported by strong materials characterization and in vitro / ex vivo bioassays.

I thrive in interdisciplinary teams and I am most effective when the goal is clear: turn a promising material concept into reproducible data, a realistic prototype, and a pathway to translation. I prefer clean experimental design over complexity — tight controls, fast learning loops, and results you can trust. Through this blog I share my thoughts on these topics, introduce my research, and try to explain why the work matters.


Professional Experience

Apr 2026 – Present

Postdoctoral Researcher

University of Zurich, Department of Chemistry — Zurich, Switzerland

Designing and developing polymer composites based on superhydrophobic 1D silicone nanofilaments for a range of applications.

Sep 2025 – Apr 2026

Consultant

Cortical Solutions, LLC (USA) — Remote / Part-time

  • Provided technical consulting on hemocompatible coating concepts under confidentiality; authored patent-style technical documentation and experimental rationale.
  • Proposed coating performance hypotheses and validation readouts (surface analytics and hemocompatibility screening) to support go/no-go decisions and IP strategy.

Sep 2024 – Oct 2025

Postdoctoral Researcher

Sabancı University, Microfluidics and Microthermal Systems Lab — Istanbul, Türkiye

  • Developed microfluidic clot-on-a-chip systems to study cavitation-assisted thrombolysis under controlled flow conditions.
  • Translated experimental findings into testable design parameters and documented results in project reports.
  • Supervised graduate students and supported project coordination.
  • Contributed to a Class III medical device project proposal (TRL-3 to TRL-5) by drafting preclinical validation concepts — study logic, endpoints, and test-setup design.

Feb 2025 – Apr 2025

Visiting Researcher

University of Strasbourg, ICube Laboratory — Strasbourg, France

Project secondment under the HORIZON TMA MSCA Staff Exchanges programme “Micro-FloTec” (Project no. 101082394). Contributed to deliverables, reporting, and partner liaison across sites.

Mar 2024 – Jun 2024

Postdoctoral Researcher

Sabancı University Nanotechnology Research and Application Center (SUNUM) — Istanbul, Türkiye

  • Developed nanoparticle systems for drug delivery and bone repair; performed mammalian cell culture and molecular assays.
  • Supported manuscript development, project proposal writing, provisional patent application filing, and internal scientific review.

Sep 2019 – Jan 2024

Research Assistant

Sabancı University Nanotechnology Research and Application Center (SUNUM) — Istanbul, Türkiye

  • Led experimental work on polymeric nanoparticles for ocular delivery, hydrogels, and metal-ion–doped hydroxyapatites.
  • Coordinated day-to-day execution across interdisciplinary projects — materials synthesis, characterization, and biological evaluation.

Jun 2019 – Aug 2019

Research Intern

New York University, Structural DNA Nanotechnology Lab — New York, USA

Trained in structural DNA nanotechnology protocols and laboratory workflows.

Sep 2018 – Aug 2019

Research Assistant

Istanbul Technical University, ITU-MEMS Laboratory — Istanbul, Türkiye

Conducted cleanroom microfabrication and materials characterization; contributed to conductive elastomer composite development.


Education

Sep 2019 – Jan 2024

Ph.D., Materials Science and Nano Engineering

Sabancı University — Istanbul, Türkiye

Sep 2014 – Jun 2018

B.Sc., Bioengineering (Honors)

Yıldız Technical University — Istanbul, Türkiye

See my full record on the Publications page.